Scientists probing life’s deepest origins have uncovered evidence that the first free-living cells may have emerged not once, but twice. The findings suggest a striking possibility: life may share one ancient genetic code, yet have undergone two separate transitions into free-living existence.| More info

Before seedlings can photosynthesize, they depend on fatty acids—and on peroxisomes to process them. Researchers discovered that the protein PEX11 not only helps these structures divide but also controls their size during early growth. When key genes were altered, peroxisomes grew abnormally large, suggesting internal vesicles normally keep them in balance. Remarkably, a yeast version of the protein fixed the problem, pointing to a deeply conserved mechanism across species.| More info

Researchers have revealed how bacteria precisely control the genes that trigger cell division. The study shows that the MraZ protein, which normally forms a donut-shaped structure, must bend and partially break apart to bind key DNA sequences that activate division genes. Using cryo-electron microscopy, scientists captured this interaction in remarkable detail. The mechanism appears to be widespread across bacteria, offering a new window into how microbes regulate growth.| More info

Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins switching states at the right time, scientists could rapidly select the best-performing variants. The technique produced new light-sensitive proteins that respond to different colors and improved optogenetic systems. It even evolved a protein that behaves like a tiny logic gate, activating genes only when two signals are present.| More info

A large genetic study shows that many people carry DNA sequences that slowly expand as they get older. Common genetic variants can dramatically alter how fast this expansion happens, sometimes multiplying the pace by four. Researchers also identified specific DNA expansions linked to severe kidney and liver disease. The findings suggest that age-related DNA instability is far more common than previously realized.| More info

A mucus-penetrating mosaic nanoparticle vaccine triggers broad nasal immunity against diverse coronaviruses, including evasive SARS- and MERS-like strains.| More info

An entropy-stabilized catalyst uses atomic disorder to break down CF4, a semiconductor gas over 6,000 times more climate-warming than carbon dioxide.| More info

Researchers created a new type of spin glass made of atoms and photons and used it to increase the memory capacity of simple artificial intelligence systems.| More info

A magnetic composite distributes nano-interfaces throughout its bulk, scaling the spin Seebeck effect for more effective conversion of waste heat into electricity.| More info

Researchers co-design engineered semiconductors and metasurfaces to build powerful optical device.| More info